… Mice and rats synthesize testosterone through the Δ 4 … (PGs) from arachidonic acid (AA). The
main steps of the … kg) inhibited the masculinization of male genitalia in GD18 embryos when …

… in vivo and its metabolites are involved in inflammation and … the synthesis and secretion of
testosterone in animal studies, … effects or associated with key confounders at p < 5 × 10 −8 . …

… cascade is involved in the conversion of arachidonic acid (AA… sinus and external genitalia,
testosterone is rapidly and … exposure of pregnant rats during the masculinization window (15.5…

… pathway and the effects of NSAID exposure on embryonic … remains unknown about how
NSAIDs are implicated in the formation of … in mice but could be reversed by arachidonic acid …

… COXs are involved in the conversion of arachidonic acid to … In mice, indomethacin has been
shown to inhibit masculine … and mortality, we exposed zebrafish embryos to drugs from 0 to 6 …

… to testosterone itself, other aspects related to masculinizing-… 20-hydroxyeicosatetraenoic
acid (20-HETE), an arachidonic acid … 951 that testosterone administration to female mice for 8 …

… 144 cultured mouse embryonic day (E) 15.5 genitalia slices … involvement of various cell
types 220 in the testis. Macrophages within the fetal and adult testis facilitate normal testosterone …

… testosterone were apparent in mice with prepubertal depletion of COUP-TFII. LMWPs, however,
are associated … The WD develops in both the male and female embryo as part of the first …

… epigenomic changes in a mouse PCOS model with similarities to … Testosterone opposes
insulin effects on subcutaneous fat … , thereby releasing masculinizing genes from epigenetic …

… Interestingly, estrogen signalling is also implicated in penis … ED is correlated with circulating
testosterone and estrogen … function in NOS mutant mice from the studies mentioned above. …